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Yichen Cao, Ph.D.
Direct Phone: (312) 222-7509
Direct Fax: (312) 222-7510
E-mail: Email me
Yichen Cao, who holds a Ph.D. in pharmaceutical sciences, is a Technical Advisor at Rakoczy Molino Mazzochi Siwik LLP.
Dr. Cao assists with preparation of opinions in the pharmaceutical, chemical, and related fields. He also provides technical litigation support in a wide range of cases, including Hatch-Waxman pharmaceutical cases. Dr. Cao has experience in the field of pharmaceutical dosage form design, controlled release mechanisms, pharmaceutical manufacturing and processing, active pharmaceutical ingredient (API) process development, analytical testing, stability work, pharmacokinetics, pharmacology and related fields.
Previous Experience
Prior to joining Rakoczy Molino Mazzochi Siwik LLP, Dr. Cao worked as a scientist at Coldstream Laboratories, Inc. where is work included formulation development for early safety studies, prototype formulations for clinical trials, preliminary process development, and commercial formulation development. Prior to obtaining his Ph.D., he held a position as a graduate research assistant at University of Kentucky in the laboratory of Professor Bradley Anderson where he obtained considerable experience with peptides, including peptide folding in organic solvents and the synthesis and characterization of peptides.
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Education
- University of Kentucky, Ph.D., Pharmaceutical Sciences, 2008
- Beijing University, B.S., Chemistry, 1998
Professional and Community Organizations
- American Association of Pharmaceutical Scientists
Articles and Presentations
Y. Cao, T.-X. Xiang, and B.D. Anderson; Development of Structure-Lipid Bilayer Permeability Relationships for Small Organic Molecules and Peptides; Molecular Pharmaceutics, 2008, 5(3), 371-388.
S.S. Rane, Y. Cao, and B.D. Anderson; Quantitative Solubility Relationships and the Effect of Water Uptake in Triglyceride/Monoglyceride Microemulsions; Pharmaceutical Research, 2008, 25(5), 1158-1174.
Y. Cao, M. Marria, and B.D. Anderson; Predictive Relationships for the Effects of Triglyceride Ester Concentration and Water Uptake on Solubility and Partitioning of Small Molecules into Lipid Vehicles; Journal of Pharmaceutical Sciences. 2004, 93(11), 2768-2779.
P.A. Koutentis, Y. Chen, Y. Cao, T.P. Best, M.E. Itkis, L. Beer, R.T. Oakley, A.W. Cordes, P. Brock, and R.C. Haddon; Perchlorophenalenyl Radical; J. Am. Chem. Soc. 2001, 123, 3864-3871.
Y. Cao and B.D. Anderson; The Energetic Cost of Transferring a Glycine (G) Residue from Water to a Hydrophobic Environment in a Series of RGX Peptides Varies with the C-Terminus; AAPS 2004.
T.-X. Xiang, Y. Cao, and B.D. Anderson; Molecular Dynamics Simulation of Conformational Dynamics of Small Peptides in Carbon Tetrachloride and Water; AAPS 2004.
G.G. Z. Zhang, Y. Cao, Y. Gao, J. Han, H. Wu; In Situ Precipitation of Weak Acid in Aqueous Media: Considerations beyond Salt Selection; AAPS 2002.
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